Skip to main content
Clinical Trials/ISRCTN43866427
ISRCTN43866427CompletedNot Applicable

A randomised study of continuous infusional 5-fluorouracil (5FU) with or without bolus mitomycin-C in patients with advanced oesophago-gastric cancer

The Royal Marsden NHS Foundation Trust (UK)0 sites254 target enrollmentStarted: August 19, 2002Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
254

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Sex
All

Inclusion Criteria

  • 1. Histological evidence of metastatic carcinoma of the oesophagus or stomach
  • 2. Histological evidence of locally advanced oesophageal or gastric carcinoma, not amenable to surgery or radiotherapy and for whom high dose chemotherapy or more intensive chemotherapy is not appropriate, normally around the age of 60

Exclusion Criteria

  • 1. Intra-cerebral metastases
  • 2. History of other malignancy (apart from adequately treated non-melanotic skin cancer or carcinoma in situ of the uterine cervix)
  • 3. Uncontrolled angina pectoris or clinically significant cardiac dysrhythmias
  • 4. Pregnancy
  • 5. Any psychological condition precluding informed consent

Investigators

Sponsor
The Royal Marsden NHS Foundation Trust (UK)

Similar Trials