ISRCTN43866427CompletedNot Applicable
A randomised study of continuous infusional 5-fluorouracil (5FU) with or without bolus mitomycin-C in patients with advanced oesophago-gastric cancer
The Royal Marsden NHS Foundation Trust (UK)0 sites254 target enrollmentStarted: August 19, 2002Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 254
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Histological evidence of metastatic carcinoma of the oesophagus or stomach
- •2. Histological evidence of locally advanced oesophageal or gastric carcinoma, not amenable to surgery or radiotherapy and for whom high dose chemotherapy or more intensive chemotherapy is not appropriate, normally around the age of 60
Exclusion Criteria
- •1. Intra-cerebral metastases
- •2. History of other malignancy (apart from adequately treated non-melanotic skin cancer or carcinoma in situ of the uterine cervix)
- •3. Uncontrolled angina pectoris or clinically significant cardiac dysrhythmias
- •4. Pregnancy
- •5. Any psychological condition precluding informed consent
Investigators
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