ISRCTN27478455已完成不适用
A randomised study of continuous infusional 5-fluorouracil with or without bolus mitomycin-C in patients with advanced colorectal cancer
The Royal Marsden NHS Foundation Trust (UK)0 个研究点目标入组 200 人开始时间: 2002年8月19日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Histological evidence of metastatic adenocarcinoma of the colon or rectum not amenable to surgery or radiotherapy
- •2. Patients evaluable for response must have bi-dimensionally measurable disease
- •3. Patients with no measurable disease
- •4. Adequate bone marrow function
- •5. Serum creatinine within normal range
- •6. Life expectancy of greater than 3 months
- •7. Eastern Cooperative Oncology Group (ECOG) performance status 0-2
排除标准
- •1. History of other malignant disease other than non melanotic skin cancer or carcinoma in situ of the cervix
- •2. Prior treatment with any cytotoxic agent except adjuvant chemotherapy completed more than 12 months from randomisation
- •3. Intracerebral metastases or meningeal carcinomatosis
- •4. Medical contraindications to treatment
研究者
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