Evaluation of Potentially Bioactive Foods With Respect to Cardiometabolic- and Cognitive Test Variables
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy Subjects
- Sponsor
- Lund University
- Enrollment
- 18
- Locations
- 1
- Primary Endpoint
- Glucose tolerance
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The overall goal is to increase the knowledge that can be used for the development of food products with antidiabetic properties, with the aim of facilitating healthier food choices for people. More specifically, the primary aim of this project is to evaluate the effects of different varieties of quinoa on postprandial glucose tolerance and subjective appetite markers. The crossover, randomised dietary intervention study will be conducted in healthy adults.
Investigators
Anne Nilsson
Associate professor
Lund University
Eligibility Criteria
Inclusion Criteria
- •BMI of 20-28
- •age between 18-40 years
- •consume a diet in accordance with Nordic Nutrition Recommendations
Exclusion Criteria
- •not vegan
- •metabolic diseases (such as diabetes)
- •Gastro intestine tract problems or irritable bowel syndrome
- •known food allergies of intolerances
- •antibiotics should not have been consumed during the last 4 weeks
- •probiotics should not have been consumed during the last 4 weeks
Outcomes
Primary Outcomes
Glucose tolerance
Time Frame: 3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes
Capillary blood glucose concentrations are measured repeatedly after test products consumed at breakfast. The postprandial incremental glucose area under the curve is used as a measure of glucose tolerance.
Secondary Outcomes
- Subjective appetite sensations (hunger, satiety, and desire to eat)(3 hours. Fasting (time =0 minutes), 30 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes)
- serum insulin(3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes)