NCT05818644已完成不适用
Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children: a Multicenter, Retrospective, Observational Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 583
- 试验地点
- 1
- 主要终点
- Graft survival
研究概览
简要总结
The goal of this observational study is to investigate the incidence, current management practices, and outcomes in pediatric patients with HAC after liver transplantation.
Research question:
- What are the overall incidence of HAC and the effectiveness of all treatment strategies for HAC after pediatric LT?
- What are the current management practices in the experience of centers, anticoagulant therapy, screening protocol, and assessment criteria for HAC after pediatric LT?
The burden of participation is considered to be minimal, and limited to the questionnaires.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 0 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver transplantation between January 1st 2002 and January 1st 2022, diagnoses of HAC after LT
- •The age of the patient is below 18 years at the time of diagnosis and intervention
- •The date of diagnosis of HAC or intervention was before January 1st
- •HAC occurring after first or subsequent LTs are included.
排除标准
- 未提供
研究组 & 干预措施
Conservative treatment
Surgical revascularization
Endovascular revascularization
Re-transplantation
结局指标
主要结局
Graft survival
时间窗: 1-1-2001 and 1-1-2023
Graft survival is defined as a functioning graft from transplantation to the end of follow-up data, re-transplantation, or death, whichever occurs first.
Patient survival
时间窗: 1-1-2001 and 1-1-2023
Patient survival is defined from the date of the primary LT until date of death. Causes of re-transplantation or death will be recorded.
次要结局
- Incidence(1-1-2001 and 1-1-2023)
- Technical success(1-1-2001 and 1-1-2023)
- Intra- and post-procedural complications(1-1-2001 and 1-1-2023)
- Primary and secondary patency(1-1-2001 and 1-1-2023)
- Anticoagulant therapy after transplantation and after interventions(1-1-2001 and 1-1-2023)
- Center specific screening protocol(1-1-2001 and 1-1-2023)
- Center specific diagnostic criteria(1-1-2001 and 1-1-2023)
- Center specific radiological follow up(1-1-2001 and 1-1-2023)
研究者
研究点 (1)
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