Assessment of Bone Mineral Density During Pregnancy
Phase 1
Completed
- Conditions
- Bone Mineral Density Quantitative Trait Locus 3
- Interventions
- Radiation: calcaneal quantitative ultrasound assessment
- Registration Number
- NCT02480023
- Lead Sponsor
- Ain Shams University
- Brief Summary
BMD at peripheral sites typically heel is measured by Ultrasound densitometry at Ain Shams Maternity hospital.
- Detailed Description
Consecutive patients with singleton pregnancies between 36 and 39 weeks booked at a general obstetric clinic in a regional hospital will be recruited for the study. The obstetric department is a tertiary referral center in the region and part of a university teaching unit which catered to an annual delivery of around 10,000 women. A group of first trimester pregnant women with nearly the same age is recruited as controls.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 173
Inclusion Criteria
- females during 3rd trimister
Exclusion Criteria
- Secondary causes of bone loss such as hyperparathyroidism.
- Co-morbidities that would interfere with bone metabolism as clinically significant liver or renal disease.
- Physical or orthopedic disabilities that would place the subject at risk or limit their ability to perform US.
- Taking medication known to affect bone including steroid hormones.
Histories of smoking and use of oral contraceptives (OCs) are not exclusion criteria.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description healthcare calcaneal quantitative ultrasound assessment QUS for calcaneus bone of right foot will be done for this group of Pregnant women at the third trimester
- Primary Outcome Measures
Name Time Method Bone mineral density loss during pregnancy that is detectable by quantitative ultrasound at the os calcis. 6 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of medicine, ain shams university
🇪🇬Cairo, Al Qahirah, Egypt