Effect of vitamin D on renin angiotensin system in heart failure patients
Phase 4
- Conditions
- Circulatory System
- Registration Number
- PACTR201908774181973
- Lead Sponsor
- rabta hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
adults > 18 years
heart failure with left ventricular ejection fraction =< 40%
either ischaemic or non ischaemic origin
clinically stable (NYHA 1 or 2 , no signs of peripheric poor perfusion and systolic blood pressure >= 90 mmhg)
blood concentration of vitamin D =< 50 nmol/l
Exclusion Criteria
non inclusion criteria
heart faiture decompensation and worsening clinical status, cardiogenic schock
renal insufficiency with cockroft formula creatinin claerance =< 15 ml/mn
baseline calcemia > 2.6 mmol/l
baseline blood concentration of vitamin D > 50nmol/l
exclusion criteria
calcemia > 2.6 mmol/l before the second administration of vitamin D
blood concentration of vitamin D > 50nmol/l before the second administration of vitamin D
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method