Dosimetric Comparison of Three Radiation Techniques for Hypofractionated Whole Breast Radiotherapy in Early Breast Cancer

Not yet recruiting

• Conditions: Breast Cancer

• Registration Number: NCT05394194
• Lead Sponsor: Sohag University

Brief Summary

We aim to compare three different radiation delivery techniques, namely three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated radiation therapy (VMAT) in left-sided early breast cancer patients.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2022-05
• Study First Submitted: 2022-05-24
• Study First Submitted QC: 2022-05-24
• Last Update Submitted: 2022-05-24
• Study First Posted: 2022-05-27
• Last Update Posted: 2022-05-27
• Study Start: 2022-07-20
• Primary Completion: 2024-07-01
• Study Completion: 2025-08-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• left sided early breast cancer patients. Should have histopathological prove to have invasive breast cancer. Operated by breast conservative surgery. Have no associated comorbidities

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Exclusion Criteria

• locally advanced breast cancer. Patients who have total mastectomy. Patients who had previous chest irradiation or known comorbidities.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of coverage of planned target volume(PTV) among the three plans.	1 year	PTV coverage in dose is compared among the three plans.
Comparison of doses to organs at risk among the three plans.	1 year	mean dose of the heart, lung volume receiving 20Gy, esophageal doses will be compared among the three plans

Secondary Outcome Measures

Name	Time	Method
Comparison of target homogeneity among the three plans.	1 year