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Current situation and clinical treatment of Korean medicine in women with polycystic ovary syndrome

Not Applicable
Recruiting
Conditions
Diseases of The genitoruinary system
Registration Number
KCT0003251
Lead Sponsor
Dongshin Korean Medilcine Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
19
Inclusion Criteria

1. Woman aged over 20 years
2. Those who satisfy the criteria of Polycystic Ovary Syndrome based on the Rotterdam Standard in 2003 and satisfy one of the following three criteria a) and one or more of b) and c)
a) Menstrual irregularity or amenorrhea (menstruation was less than 8 or exceeded 35 days in the past year)
b) Clinical hyperandrogenism or hyperandrogenemia(If the total testosterone concentration is greater than 0.68 ng / ml, the free testosterone concentration is greater than 1.72 pg / ml, or the modified Ferriman- Gallwey score is greater than or equal to 6)
c) Polycystic ovary : On ultrasonography examination, one ovary had 12 or more follicles 2 to 9 mm in diameter or more than 10 mL of ovarian volume
3. Who voluntarily signed to the informed consent form
4. Who can trust the researcher, cooperate throughout the study period, comply with restrictions

Exclusion Criteria

1. Who diagnosed with pituitary disease, hypothalamic disease, thyroid dysfunction, uterine tuberculosis, etc., which is a cause of menstrual irregularity.
2. Who diagnosed with hyperprolactinemia, hyperthyroidism, and ovarian dysfunction at the screening visit
3. Who taking another medicine such as Antidepressant, Anti-serotonin, Antipsychotic

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Anti Mullerian Hormone(AMH);Follicle stimulating hormone(FSH);Luteinizing hormone(LH);Estradiol(E2);Frequency of menstruation
Secondary Outcome Measures
NameTimeMethod
sonograhpy results;Quality of life;Pattern identification questionnaire;Adverse events;Blood Urea Nitrogen(BUN), Creatinine(Cr), Aspartate Aminotransferase(AST), Alanine Aminotransferase(ALT), Gamma-Glutamyl Transferase(GGT), Sodium(Na), Potassium(K), Chloride(Cl), Complete Blood Cell Count(CBC), Total/Free testosterone, Prolactin;Economic analysis
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