NCT04390256已完成不适用
Remineralization of Early Carious Lesion Using Natural Agents Versus Bioadhesive Polymers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Remineralization of enamel
研究概览
简要总结
This study will be conducted to evaluate:
- The remineralization potential of natural agents (egg shell powder and clove extract) versus bioadhesive polymers (carbopol and carboxymethyl cellulose) with or without PH cycling using microhardness test.
- The clinical efficacy of all agents in patients with early carious lesions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Criteria related to patient:
- •Age's eligible for trial was 18- 30 years.
- •Patient able to read and sign the informed consent form.
- •Cooperative patient who are willing to participate and able to continue the schedule time of wok keep good oral hygiene throughout the study.
- •Healthy volunteers.
- •Patient with moderate and high caries index.
- •Criteria related to tooth:
- •Patient with at least 2 white lesions (WSL) detected clinically on the buccal surface of permanent anterior teeth, one on each side. WSL selected either due to caries or orthodontic treatment (just following deboning).
- •Teeth with score1, 2, 3 according to ICDAS II.
- •Absence of preoperative pain, no mobility & tenderness on percussion.
- •Radiographically, the pre-operative inclusion criteria were absence of internal or external resorption, no periapical radiolucencies and no widening of periodontal ligament space..
排除标准
- •Criteria related to patient:
- •Patient with Rampant uncontrolled caries.
- •Patient with compromised medical history.
- •Pregnant or breast feeding females.
- •Heavy smoker.
- •Patient who currently received extensive fluoride regiments for treatment of WSL.
- •Patients who planned to move within 3 months of enrollment.
- •Patient with evidence of xerostomia.
- •Criteria related to tooth:
- •Teeth with score 4, 5 according to ICDAS II.
- •Teeth with periapical pathology, internal or external resorption or exhibiting any symptoms of pulp pathology.
- •Teeth with questionable vitality or have root canal therapy.
- •Teeth have been pulp capped.
- •Teeth with periodontal pocket and bleeding on probing.
- •Cracked teeth.
结局指标
主要结局
Remineralization of enamel
时间窗: 3 months
Remineralization of enamel using Vista scan
次要结局
未报告次要终点
研究者
Marwa Mohamed
Ass. lecturer
Al-Azhar University
研究点 (1)
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