in situ studie to analzye the remineralizing efficacy of a new carbonate hydroxyapatite nanocrystals containnig toothpaste
- Conditions
- K02Dental caries
- Registration Number
- DRKS00011653
- Lead Sponsor
- Klinik für Zahnerhaltung, Parodontologie und Präventive Zahnheilkunde,Universitätsklinikum der RWTH Aachen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
•give written informed consent;
•be between the ages of 18 and 70;
•be in good general health;
•agree not to participate in any other clinical study for the duration of this study;
•agree to refrain from using any non-study oral hygiene products including: toothbrushes, dentifrices, mouth rinses, tooth whitening products or floss for the study duration other than their usual toothbrush and toothpaste which will be used during the Acclimation period between each visit;
•have a minimum of 20 teeth (excluding third molars);
•agree to return for the scheduled clinical visits and follow study procedures;
•active participation in another oral/dental products clinical study;
•current severe chronic illness or infectious disease;
•drug or alcohol abuse;
•eating disorders,
•pregnancy or breast feeding;
•antibiotic use (2 months before and during study) or medication reducing salivary flow;
•intake of other medications that might have an impact on the outcome;
•bad oral cleanliness, no agreement to comply with study design;
•known allergic reactions to any of the test substances;
•other allergic reactions to dental materials or oral hygiene products;
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Before and after each experimental period the specimens are retrieved to assess lesion depth and mineral content by transversal microradiography (TMR).
- Secondary Outcome Measures
Name Time Method