Cardiovascular Impact of Obstructive Sleep Apnea Treatment in Normotensive Patients

Phase 4

Completed

• Conditions: Obstructive Sleep Apnea
• Interventions: Device: CPAP

• Registration Number: NCT00741520
• Lead Sponsor: University of Sao Paulo

Brief Summary

Recent evidences suggest that obstructive sleep apnea (OSA) can contribute to cardiovascular disease even in the absence of hypertension. However, there are few data regarding the impact of OSA on the preHypertension and Masked Hypertension in apparently normotensive patients with OSA as well as the impact of treatment with continuous positive airway pressure.

Detailed Description

Not available

Study Timeline

• Status Verified: 2008-08
• Study Start: 2008-08
• Study First Submitted: 2008-08-25
• Study First Submitted QC: 2008-08-25
• Study First Posted: 2008-08-26
• Primary Completion: 2010-03
• Study Completion: 2010-07
• Last Update Submitted: 2010-10-27
• Last Update Posted: 2010-10-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 36

Inclusion Criteria

• Severe OSA patients

Exclusion Criteria

• Smoking
• Sustained Hypertension
• Heart failure
• Diabetes
• Renal diseases
• Under use of any medication
• Under treatment for OSA

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	CPAP	Control group
2	CPAP	CPAP

Primary Outcome Measures

Name	Time	Method
Office Blood Pressure		Evaluation of PreHypertension

Secondary Outcome Measures

Name	Time	Method
24 Hour Ambulatory Blood Pressure Monitoring		Evaluation of Masked Hypertension

Trial Locations

Locations (1)

Heart Institute (InCor); 🇧🇷 Sao Paulo, Brazil