The effect of long-term olive-oil based parenteral lipid use on immune functions: a patient-control study
Completed
- Conditions
- immune modulation by lipids100254771002766510002252
- Registration Number
- NL-OMON32714
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
view page 11 of the protocol
Exclusion Criteria
view page 11 of the protocol
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Leukocyte counts (with leukocyte differentiation)<br /><br><br /><br>Leukocyte functions:<br /><br>*oxygenradical production by neutrophils<br /><br>*expression of neutrophil and monocyte cell surface activation markers<br /><br>*Bacterial killing capacity of neutrophils<br /><br>*stimulus-induced ex-vivo cytokineproduction by PBMCs<br /><br><br /><br>Candidagrowth in cel-free serum<br /><br><br /><br>(anti-)oxidant status (Vitamin A,C, E, Selenium, glutathion)<br /><br>oxidatieve damage (TBARS (indicative for lipid-peroxidation) and protein<br /><br>carbonyls (indicative for protein damage) </p><br>
- Secondary Outcome Measures
Name Time Method <p>none</p><br>