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Microbial Composition of Breast Milk Collected From Healthy Turkish Women

Completed
Conditions
Microbial Community in Breast Milk
Registration Number
NCT04072627
Lead Sponsor
Hacettepe University
Brief Summary

Breast milk is an optimal source of nutrients for newborns as well as a potential source of bacteria for the intestinal microbiota. However, there are limited number of studies evaluating the relationship between maternal nutrition, breast milk and neonatal intestinal microbiota.

Detailed Description

The study was conducted on a total of 20 healthy women following at Obstetrics and Gynecology Department of Gülhane Education and Research Hospital in Ankara Health Sciences University. Sociodemographic characteristics, anthropometric measurements, breastfeeding characteristics were evaluated in the third trimester of the women who underwent routine prenatal care. Breast milk samples were obtained at 16.day postpartum during lactation.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
20
Inclusion Criteria
  • Singleton pregnancy
  • Age 19-35 years
  • At weeks of 30-36 gestation
  • No history of acute or chronic diseases
  • Term delivery
Exclusion Criteria
  • Alcohol use
  • Smoking
  • Gestational diabetes
  • Type 1 and 2 diabetes
  • Preeclampsia
  • Polycystic ovary
  • Syndrome
  • Thyroid and parathyroid disease
  • Metabolic bone or kidney disease
  • Abnormal liver function
  • Multiple pregnancy
  • Premature and postmature labor
  • Having chemotherapy
  • Taking drugs such as antibiotics and probiotics

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Microbial abundance and diversityat 16 day postpartum

The microbial composition of the breast milk samples was determined by 16S rRNA (ribosomal ribonucleic acid) gene sequencing analysis.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hacettepe University

🇹🇷

Ankara, Turkey

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