A pilot study to explore the bioavailability of UMP enriched products in healthy volunteers

Recruiting

• Conditions: ridine bloedbeeld na uridine monofosfaat inname; Uridine bioavailability; uridine blood levels

• Registration Number: NL-OMON36006
• Lead Sponsor: Danone Research - Centre for Specialised Nutrition

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

-Male
-Age 50-70 years, inclusive
-BMI 18- 28kg/m2, inclusive
-Written informed consent

Exclusion Criteria

-Any condition that may interfere with the definition *healthy volunteer* according to the investigator, with special attention to the presence of liver disease, bowel disease, diarrhea and catabolism (unintended recent weight loss)
-Heavy exercise like long-distance running one week prior to the study day
-The use of RNA rich nutritional supplements (such as yeast) within a period of one month prior to the start of the study
-Unable to adhere to protocol instructions
-Alcohol or drug abuse in the opinion of the investigator
-Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
-Participation in any other studies involving investigational or marketed products concomitantly or within two weeks prior to entry into the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in blood plasma levels of uridine over time, following single intake of<br /><br>study product.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.a.</p><br>