Combining emotion recognition training with oxytocin administration: A psychobiological approach

Phase 2

Conditions: antisocial behavior
externalizing problems
10037173

Registration Number: NL-OMON49988

Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 80

Inclusion Criteria

The inclusion criteria are: male, aged 12-20, living in residential youth care
facilities, capable to read and comprehend the Dutch language, exhibit
antisocial behavior and deficits in emotion recognition skills, and provide
written informed consent.

Exclusion Criteria

The exclusion criteria are: medication for severe medical problems, presence of
severe nasal disease or history of severe nasal surgery, renal or hepatic
impairment, latex allergy or intolerance.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter is the change in emotion recognition skills from<br /><br>baseline to post-training and follow-up between the two groups (oxytocin+ERT vs<br /><br>placebo+ERT).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary parameters are the change in aggression, and delinquency from<br /><br>baseline to post-training and follow-up between the two groups (oxytocin+ERT vs<br /><br>placebo+ERT). We also examine whether psychological and environmental factors<br /><br>influence the effectiveness of the intervention.</p><br>