Clinical, microbiological, radiographical and immunological evaluation of implant surface decontamination using air polishing in the non- surgical treatment of peri-implantitis; a randomized controlled study

niversity Medical Center Groningen0 个研究点目标入组 80 人开始时间: 待定最近更新: 2024年2月28日

试验速览

暂无简介。

•The patient is = 18 years of age;
•The patient has at least one endosseous implant in the oral cavity with clinical and radiographical signs of peri-implantitis. Peri-implantitis is defined as progressive loss of marginal bone = 2mm, as compared to the baseline radiograph (after placing the definitive restoration) in combination with bleeding and/or suppuration on probing;
•The implants have been in function for at least two years;
•The patient is capable of understanding and giving informed consent.

•-Medical and general contraindications for the procedures;
•-A history of local radiotherapy to the head and neck region;
•-Pregnancy and lactation;
•-Uncontrolled diabetes mellitus (HbA1c < 7% or < 53 mmol/mol);
•-Use of antibiotics during the last 3 months;
•-Known allergy to chlorhexidine;
•-Long-term use of anti-inflammatory drugs;
•-Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
•-Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
•-Implant mobility;
•-Implants at which no position can be identified where proper probing measurements can be performed;
•-Previous surgical treatment of the peri-implantitis lesions;
•-Previous non-surgical treatment of the peri-implantitis lesions during the last 3 months (scaling or curettage)
•-Chronic bronchitis and asthma
•-Presents of natural dentition (only for patients in heamatological study)

发起方