Clinical and microbiological evaluation of the dental canal

Not Applicable

Recruiting

• Conditions: Pulpitis; Dental Pulp; Necrosis; Abscess; C07.793.901; A14.549.167.237; Periapical Granuloma; Periapical Periodontitis; Retreatment; Periapical Tissue

• Registration Number: RBR-9xpg3j
• Lead Sponsor: Faculdade de Odontologia de Piraicaba-Universidade Estadual de Campinas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-23
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with systemic health condition ASA I or II. Permanent teeth with pulp necrosis; pulp vitality; pulpitis; endo-perio lesions; endodontic treatment failure; periapical lesion; periodontal tissues.

Exclusion Criteria

use of antifungals; antibiotics; immunosuppressants; and antivirals (up to 3 months previously to the study); and teeth with root fracture.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The endodontic microbiota and its virulence factors are expected to be evaluated using Nested-PCR, Checkerboard, next-generation sequencing, PCR, LPS, and LTA methods. We will observe if there was a decrease in the microorganisms and their virulence factors after the several stages of the endodontic treatment/retreatment/surgery.;It is expected to identify the host immune response using ELISA. We will observe the host immune response to infection and after the various stages of endodontic treatment/retreatment/surgery.

Secondary Outcome Measures

Name	Time	Method
o secondary outcomes are expected.