Clinical, virological, immunological, psychosocial and epidemiological consequences of the human MonkeypoX Virus outbreak, a PROspective observational cohort study (pro-MPX)
- Conditions
- monkey-pox1004743810040792
- Registration Number
- NL-OMON51810
- Lead Sponsor
- GGD Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 300
For cases
I. Laboratory confirmed MPXVID, or
II. A presumptive MPXVID case with pending laboratory confirmation
For controls
• Individuals without proctitis and MPXVID-related symptoms
For cases:
• Presumptive cases with subsequent negative test for MPXV (can subsequently be
included as control);
• Being under the age of 16 years old;
• Unlikely to comply with the study procedures, as deemed by the recruiting
research doctor/nurse;
• Mental disorder that in the view of the investigator would interfere with
adherence to the study procedures, or the decision to participate in the study;
• Investigators or otherwise dependent persons;
• Living in long term care facility.
For controls:
• Positive test result for MPXV at baseline (day 0)
• Being under the age of 16 years old;
• Unlikely to comply with the study procedures, as deemed by the recruiting
research doctor/nurse;
• Mental disorder that in the view of the investigator would interfere with
adherence to the study procedures, or the decision to participate in the study;
• Investigators or otherwise dependent persons;
• Living in long term care facility.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Objective<br /><br>1: What is the time to resolution of symptoms among patients with symptomatic<br /><br>MPXVID?<br /><br><br /><br>Outcome measure<br /><br>1: The time between appearance of the first lesions and the day on which all<br /><br>skin lesions are epithelialized and crusts fall off, and all systemic symptoms<br /><br>(incl. proctitis) have resolved.</p><br>
- Secondary Outcome Measures
Name Time Method