Risk factors of Asherman's syndrome

Not Applicable

• Conditions: Asherman's syndrome; Urological and Genital Diseases; Asherman's syndrome, intrauterine synechiae

• Registration Number: ISRCTN14987772
• Lead Sponsor: General University Hospital in Prague

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-15
• Last Update Posted: 30 March 2021
• Study Completion: 2025-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Clinical suspicion of Asherman's syndrome verified by hysteroscopy or previous intrauterine procedure with follow-up hysteroscopy without intrauterine adhesions

Exclusion Criteria

1. Other uterine pathology (e.g. submucosal leiomyoma, adenomyosis, and cervical lesion)
2. Hormonal therapy <1 month prior to the hysteroscopy
3. Gynecological malignancy in last 12 months

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Characteristics of endometrial reactivity to insult measured using single-cell analysis during the indicated hysteroscopy at baseline

Secondary Outcome Measures

Name	Time	Method
Reproductive outcomes of patients with Asherman's syndrome measured using questionnaires at baseline, 6, 12, 18, 24, 30, and 36 months