Characteristics of root canal instrumentation with enlargement of the apical forame

Not Applicable

Recruiting

• Conditions: Dental Pulp Necrosis; Periapical Periodontitis; C07.793.237

• Registration Number: RBR-3qzk3nw
• Lead Sponsor: Faculdade de Odontologia da Universidade Federal de Minas Gerais

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-15
• Last Update Posted: 29 April 2024
• Study Completion: 2026-07-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients aged 18 years or over; of both sexes; diagnosed with pulp necrosis and apical periodontitis in upper or lower first and/or second molars

Exclusion Criteria

Use of some antibiotics and anti-inflammatory drugs in the three months before endodontic therapy; those who have already started instrumentation of the canals previously and/or present concomitant periodontal involvement in the tooth in question; teeth with root fractures, fused roots, incomplete rhizogenesis, wide foramina whose initial apical instrument in the MV canal is greater than K #20

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The reduction in intraradicular bacterial load after root canal instrumentation will be analyzed using molecular detection methods (real-time PCR).;We will observe the expression of inflammatory cytokines, through analysis using molecular detection methods (real-time PCR).;The incidence of postoperative pain after root canal instrumentation will be analyzed, using a five-level scale.

Secondary Outcome Measures

Name	Time	Method
o secondary outcomes are expected.