NCT05705011已完成不适用
Frailty, Cognitive Function and Health-related Quality of Life in Older Adults With Advanced Chronic Kidney Disease: Mortality and Dialysis Initiation, a Prospective Cohort Study.
Grigore T. Popa University of Medicine and Pharmacy1 个研究点 分布在 1 个国家目标入组 240 人开始时间: 2019年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Time to initiate dialysis.
研究概览
简要总结
This observational study explores the impact of cognitive impairment and frailty in older adults with advanced chronic kidney disease ].
The main question[s] it aims to answer are:
- What determines the time to initiate dialysis? Cognitive impairment or frailty?
- What does predict the time to death? Presence of frailty or cognitive impairment?
- What does correlate strongly with time-low health-related quality of life? frailty or cognitive impairment?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients age 65 years or older.
- •CKD stage 4 and 5 who were identified by two consecutive measurements of estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2 separated by more than 3 months.
排除标准
- •Patients younger than 65 years old.
- •Chronic kidney disease stages 1,2, and
- •Dialysis dependence
- •History of kidney transplantation.
- •Initial visit with the health care provider.
- •Recent acute kidney injury.
- •Patients who had been hospitalized for more than 2 months before the visit (because long hospitalization might affect the degree of frailty)
- •Patients with myocardial infarction and cerebrovascular accident 3 months before the assessment
- •Patients who are blind or with limb amputation.
- •Patients who refuse to participate.
结局指标
主要结局
Time to initiate dialysis.
时间窗: 36 months
The time from the assessment moment to start dialysis of an older adult with advanced CKD (
Time to death
时间窗: 36 months
The time from the assessment moment to death of an older adult with advanced CKD ( CKD stage 4 and 5).
次要结局
未报告次要终点
研究者
Hani Hussien
Doctor
Grigore T. Popa University of Medicine and Pharmacy
研究点 (1)
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