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Clinical Trials/NCT03840941
NCT03840941
Completed
N/A

The Effect Of Frailty Level On Balance, Cognition And Activities Of Daily Living In COPD

Hacettepe University1 site in 1 country48 target enrollmentMarch 1, 2018
ConditionsCOPDFrailty

Overview

Phase
N/A
Intervention
Not specified
Conditions
COPD
Sponsor
Hacettepe University
Enrollment
48
Locations
1
Primary Endpoint
Perform activities of daily living (ADL) will be evaluated using the Glittre ADL-test
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The investigators aim to demonstrate whether balance, cognition and activities of daily living have changed in COPD patients with and without frailty.

Detailed Description

COPD is a common, preventable and treatable disease characterized by progressive respiratory symptoms and airflow limitation. Frailty defines a clinical syndrome characterized by multiple system effects, leading to decreased functional reserve and increased sensitivity to dependence or mortality following minor stress events. Inflammation, lack of physical activity, reduced exercise efficiency and maximum oxygen uptake may contribute to the development of frailty in patients with COPD. Balance, cognition and activities of daily living are associated with COPD. This study will evaluate the effect of frailty on balance, cognition and activities of daily living in patients with COPD.

Registry
clinicaltrials.gov
Start Date
March 1, 2018
End Date
October 15, 2019
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Deniz Inal-Ince

Prof. Dr.

Hacettepe University

Eligibility Criteria

Inclusion Criteria

  • COPD patients who have been clinically stable for the last four weeks and who have not undergone drug change for the last four weeks
  • Being 55 years of age or older
  • Accepted to participate in the study (Able and wililing to complete the informed consent process)
  • Co-operate
  • Patients with COPD who are ambulant without support or an assistive device

Exclusion Criteria

  • Neurological, cardiac or orthopedic diseases
  • Other chronic diseases that may affect balance and walking

Outcomes

Primary Outcomes

Perform activities of daily living (ADL) will be evaluated using the Glittre ADL-test

Time Frame: 1st Day

Glittre ADL-test was designed specifically to assess the functional limitation in patients with COPD. Glittre ADL-test time will be considered the main outcome variable, and will be recorded in minutes (metric).

Presence of The Frailty Will Be evaluated Using The Frailty Criteria by Fried

Time Frame: 1st Day

Frailty will be identified by the presence of three or more of the following criteria unintentional weight loss (10 Ibs in past year), weakness (grip strength), self-reported exhaustion, slow walking speed and low physical activity. Patients with three or more of the criteria present were classified as frail.

Balance Assessment Using Functional Reach Test

Time Frame: 1st Day

The Functional Reach Test measures how far patient can reach forward from a normal relaxed stance.

Cognition Using MoCA-Test

Time Frame: 1st Day

Cognitive function will be evaluated with the secreening tool the Montreal Cognitive Assessment (MoCA). The MoCA is a 30-point screening tool.

Secondary Outcomes

  • Disease-Related Quality of Life Assessment(1st Day)
  • Respiratory Muscle Strength Assessment(1st Day)
  • Shortness of Breath Assessment(1st Day)
  • Exercise Capacity Using 6-Minute Walk Test(1st Day)

Study Sites (1)

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