Clinical Characteristics and Prognosis of Aortic Dissection in China (CLASSIC): a National, Multicenter, Retrospective-prospective, Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic Dissection
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Change of post-operative survival rate
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This study will construct a retrospective-prospective long-term follow-up cohort and management system for aortic dissection through a multicentre collaborative network. This study aims to investigate the disease characteristics, progression patterns, clinical features, natural course and factors affecting the disease course and prognosis of patients with aortic dissection by retrospectively collecting data and prospectively enrolling patients.
Detailed Description
This study aims to construct a retrospective-prospective long-term follow-up cohort and management system for aortic dissection through a multicentre collaborative network. The duration of the study will be divided into retrospective and prospective components. The retrospective study will collect cases of aortic dissection of different aetiologies from 2003-2022; the prospective study is expected to collect cases of aortic dissection from 2022-2030. The study is expected to assess the disease characteristics, progression patterns, clinical features, natural course and long-term prognosis of aortic coarctation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18-80 years;
- •Meet diagnostic criteria for aortic dissection.
Exclusion Criteria
- •Age \<18 years or \>80 years;
- •Women who are pregnant and breastfeeding;
- •Patients and their families refuse or are unable to sign the informed consent form.
Outcomes
Primary Outcomes
Change of post-operative survival rate
Time Frame: 3, 6, 9 month and 1, 2, 3, 4, 5 year after the surgery.
Post-operative survival rate of patients after aortic dissection surgery in 3, 6, 9 month and 1, 2, 3, 4, 5 year. The survival situation will be assessed by telephone follow-up.
Secondary Outcomes
- Change of the incidence of MACCE(3, 6, 9 month and 1, 2, 3, 4, 5 year after the surgery.)
- Incidence of any complications(5 years after the surgery.)