Effects of Two Physical Exercise Protocols on Cognition and Physical Performances in Elderly Over 80 Years

Not Applicable

Completed

• Conditions: Sedentary
• Interventions: Other: Resistance training; Other: Multicomponent training

• Registration Number: NCT01983397
• Lead Sponsor: Universidade Federal de Sao Carlos

Brief Summary

The purpose of this study is to compare the effects of different trainings on cognition and physical performances in elderly over 80 years.

Detailed Description

Purpose: To compare the effects of 16-week multicomponent and resistance trainings on cognition and physical performances related to falls in oldest old people living in community; to analyze the same variables after 6-week detraining. Method: We conducted a randomized controlled trial with 69 community elderly over 80 years, sedentary and without cognitive disorder. Participants were allocated to control, multicomponent training or resistance training group. The multicomponent group performed a protocol involving warm-up, aerobic, strength, balance and cool-down exercises. The resistance group underwent to strength exercises using six machines: leg press, chest press, calf, back extension, abdominal and rowing. The control group did not perform any intervention. The trainings had progressive intensity, lasted 16 weeks and included three 1-hour sessions per week. The participants were evaluated at baseline, at the end of 16-week training and at 6-week detraining. The assessment consisted of anamnesis, depression (Geriatric Depression Scale), cognition (Montreal cognitive assessment), dual task walking (associated to cognitive and motor tasks), balance (unipedal and tandem tests), strength of lower limbs (sit-to-stand test) and history of falls. For statistical analysis by intention to treat, we adopted a significance level of α=0.05.

Study Timeline

• Study Start: 2012-08
• Primary Completion: 2013-09
• Study Completion: 2013-09
• Study First Submitted: 2013-10-31
• Status Verified: 2013-11
• Study First Submitted QC: 2013-11-06
• Last Update Submitted: 2013-11-06
• Study First Posted: 2013-11-14
• Last Update Posted: 2013-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

• age between 80 and 95 years old
• live in community
• sedentary lifestyle
• ability to walk without help from another person with/without aid walking

Exclusion Criteria

• any cardiovascular or infectious comorbidity described in the absolute contraindications of the Physical Activity Readiness Medical Examination
• Relative contraindications of cognitive, neurological and/or musculoskeletal comorbidities which make participation in protocols impossible
• Score in mini-state examination mental below the cutoff score designated by education level.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Resistance training	Resistance training	Resistance training
Multicomponent training	Multicomponent training	Multicomponent training

Primary Outcome Measures

Name	Time	Method
Changes from baseline in balance after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, after 16 weeks of training and 6 weeks of detraining	Balance was assessed by unipedal test and tandem test.
Changes from baseline in dual task walking after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, after 16 weeks of training and 6 weeks of detraining	Dual task was assessed by Timed Up and Go test with a cognitive task (speak day of week in reverse order) and motor task (carry a cup of water).
Changes from baseline in lower limbs strength after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, after 16 weeks of training and 6 weeks of detraining	Lower limbs strength was assessed by 5 times sit-to-stand test.
Changes from baseline in cognition after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, after 16 weeks of training and 6 weeks of detraining.	Cognition was evaluated by Montreal Cognitive Assessment.

Secondary Outcome Measures

Name	Time	Method
Changes from baseline in number of falls after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.	Presence of falls was assessed by falls calendar and phone calls.
Changes from baseline in depression after 16 weeks of training and 6 weeks of detraining	Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.	Depression was assessed by abbreviated Geriatric Depression Scale.

Trial Locations

Locations (1)

Universidade Federal de São Carlos; 🇧🇷 São Carlos, São Paulo, Brazil