abij-infrarode fluorescente beeldvorming gecombineerd met radioactieve colloiden voor de schildwachtklierprocedure in borstkanker patienten.
Recruiting
- Conditions
- Breast cancer
- Registration Number
- NL-OMON22204
- Lead Sponsor
- eiden University Medical Center (LUMC)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
Breast cancer patients planned to undergo a sentinel lymph node procedure.
Exclusion Criteria
1. History of allergy to iodine, shellfish, indocyanine green or human serum albumin;
2. Pregnancy;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IR fluorescence identification ratio of the SLN, defined as the proportion of patients in whom sentinel and non-sentinel lymph nodes were identified using NIR fluorescence.<br>
- Secondary Outcome Measures
Name Time Method 1. Difference in signal-to-background ratio between patient groups;<br /><br>2. Difference in radioactive tracer uptake between patient groups;<br /><br>3. Number of identified SLNs: Fluorescence and non-fluorescence;<br /><br>4. In vivo and ex vivo fluorescence intensity of SLNs and radioactivity of the SLNs;<br /><br>5. Percutaneous lymphatic channel identification at multiple time points.