Effects of Intralymphatic Allergen Immunotherapy in treatment of allergic rhinitis
Phase 2
- Conditions
- Allergic Rhinitis.Allergic rhinitis due to pollen
- Registration Number
- IRCT20161206031256N2
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Patients with Seasonal or Perennial Allergic Rhinitis
Aggravated symptoms from mid Summer till mid Autumn for at least two years
Age :15-65 years
Positive Skin Prick Test response to Salsola Kali
Symptoms remain troublesome despite treatment
The ability to comply with study procedures
Exclusion Criteria
Past history of Autoimmune Diseases
Ongoing Systemic Immunosuppressive treatment.
The presence of Pregnancy
The presence of Immunodeficiency
The presence of Allergic Asthma
The presence of Heart Diseases
Ongoing Beta Blocker or ACE inhibitors drug usage
The presence of Malignancy
The presence of any chronic diseases
Current symptoms of Upper Respiratory Tract Infection
History of life-threatening Anaphylaxis or Angioedema
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical Symptoms, Drug Usage, Skin Prick Test, Specific IgE. Timepoint: Befor The Trial. Method of measurement: Sign And Symptoms, Antiasthmatic Drugs Usage, Skin Prick Test, Peakflowmetry and Specific IgE.
- Secondary Outcome Measures
Name Time Method Clinical symptoms, drug usage, specific IgE. Timepoint: One month after end of treatment. Method of measurement: Physical examination and peakflowmetry.