Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension. A Randomized Controlled Trial (ALPS Plus). - ALPS Plus

Institute of Liver and Biliary Sciences0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年11月13日

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•1.Age – 18-75 yrs of age
•2.Cirrhotic patients with sepsis induced hypotension defined as mean arterial pressure less than 65mm of Hg with suspected (as per history and examination) or documented evidence of infection.

•1.Patients with other causes of hypotension
•2.Patients who have already received bolus of 5% albumin or plasmalyte or >2L of fluids
•3.Patients with structural heart disease or known diastolic dysfunction or cirrhotic cardiomyopathy
•4.Patients who are on vasopressors or inotropes,
•5.Patients already receiving renal replacement therapy
•6.Patients with known chronic obstructive lung disease or congestive heart failure
•7.Patients with serum albumin below 1.5 g/dl
•8.Patients in need of surgical intervention
•9.Pregnant or lactating women
•10.Patients with a previous adverse reaction to human albumin.

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