CTRI/2020/05/025064
Recruiting
未知
Role of Albumin versus Plasmalyte A salt solution in improving Major Adverse Kidney Events within 30 days (MAKE30) in critically ill cirrhotic patients with sepsis- A Pilot Study.
Post Graduate Medical Education and Research Chandigarh0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: K77- Liver disorders in diseases classified elsewhere
- Sponsor
- Post Graduate Medical Education and Research Chandigarh
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)Adults ( \>18 years) admitted to ICU with cirrhosis and sepsis
- •2\)Hypotension (Mean Arterial Pressure (MAP) \<65mmHg)
- •3\)Lactate levels \>2 mmol/L (to pick even mild hypoperfusion)
- •4\)Clinical need for of a Central Venous Catheter (CVC) and arterial line
Exclusion Criteria
- •1\)Severe pre\-existing cardiopulmonary disease
- •2\)Active bleeding
- •3\)Cerebrovascular events
- •4\)Prior renal disease/need of renal replacement therapy
- •5\)Admission to ICU following liver transplantation, burns, cardiac surgery
- •6\)Brain death or likely brain death within 24 hours
- •7\)Previous adverse reaction to human albumin solution
Outcomes
Primary Outcomes
Not specified
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