A randomized clinical trial comparing the effect of intraovarian and subcutaneous injection of corifollitropin alfa in the Duostim protocol in infertile women with premature ovarian failure and poor responders candidates for IVF
Not Applicable
Recruiting
- Conditions
- infertility.Female infertility
- Registration Number
- IRCT20180409039247N6
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
BMI<= ??
Poor responder cases with abnormal biomarkers AFC :?_??AMH .?-?.?)<brHistory of non-response in previous cycles (less than 3 oocytes) or first ivf experience
Sperm analysis is normal or has the minimum necessary criteria for ICSI
Exclusion Criteria
History of autoimmune diseases - coagulation disorders - uterine anomalies - chromosomal and genetic disorders - chronic renal and metabolic diseases - hypo and hyperthyroidism - history of malignancy - endometriosis - history of repeated miscarriage and RIF
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number and quality of oocytes obtained. Timepoint: On the day of puncture. Method of measurement: The number of eggs obtained on the day of puncture with OPU catheter.;Number and quality of obtained embryos. Timepoint: The day after the puncture in the embryology laboratory. Method of measurement: Under the microscope in the embryology laboratory by the embryologist.
- Secondary Outcome Measures
Name Time Method