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Frequency and mechanisms of resistance to IGF-1 generation in non-GH deficient short children with low IGF-1 concentration - IGF-1 generation protocol

Conditions
Prepubertal children with stature < -2 SDS, IGF-1 < the lowest reference limit and normal growth hormone response to an ITT or glucagon test
MedDRA version: 9.1Level: LLTClassification code 10040600Term: Short stature
Registration Number
EUCTR2009-012089-30-BE
Lead Sponsor
Z Brussel
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
50
Inclusion Criteria

Prepubertal Children
Stature < - 2SDS
IGF-1 < lowest reference limit
normal GH response to ITT or Glucagon test
Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Acute illness at the moment of testing
Any chronic disease interfering with growth

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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