Role of Inflammatory markers in different grades of Diabetic Foot Ulcer
- Conditions
- Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
- Registration Number
- CTRI/2023/07/055588
- Lead Sponsor
- Dr Shaheen B Shaikh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
A total of 125 diabetic foot ulcer patients and 125 diabetic patients without foot ulcer (free from foot wounds and acute or chronic disease), admitted to surgery wards will be enrolled in the study. All wounds will be graded when they will get admitted to the hospital according to the Wagner classification system into five grades (grade I - grade V), the number of patients in each group will be 25.Foot ulcer was defined as a full-thickness skin defect that required >=14 days for healing. Cases and controls will be matched for age (±3 years), sex and duration of Diabetes.
Patients with inflammatory or infectious diseases, autoimmune
and rheumatic diseases, cancer, hematological diseases, malignancy, Pregnancy ,lactation ,Chronic inflammatory disorders, severe renal or liver failure, recent venous thromboembolism ,as well as those who were under treatment with immunodeficiency drugs , will be excluded from study . Foot ulcers caused by other conditions such as arterial insufficiency, venous insufficiency, or trauma will be excluded
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the study may provide new insights that could lead to better diagnosis, prevention, & treatment of this condition, ultimately improving the health outcomes & well-being of affected individuals.Timepoint: At Baseline, 4 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method This study can also raise the possibility that inflammatory markers might provide an adjunctive method for early detection of risk for this disease & ultimately decreases the lower limb amputation & hence decreasing the mortality & morbidity of patients with DFU.Timepoint: At Baseline, 4 weeks & 8 weeks