Do iron and vitamin B12 injections given together, improve haemoglobin in patients on haemodialysis?
- Conditions
- Health Condition 1: D509- Iron deficiency anemia, unspecifiedHealth Condition 2: D519- Vitamin B12 deficiency anemia, unspecified
- Registration Number
- CTRI/2020/11/029193
- Lead Sponsor
- Christian Medical College Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 104
All adult prevalent haemodialysis (HD) patients on HD for at least 3 months with haemoglobin
< 11 g/dL during the study period.
1. Blood transfusion, blood loss, infection or surgery or change in haemoglobin by
> 1 g/dL in the last 1 month
2. Haemoglobinopathy
3. Cirrhosis
4. Haematological malignancy, myeloproliferative disorder, HIV, HBV or HCV
infection
5. Any chronic inflammatory disorder
6. IV iron or oral/IM B12 received in the last 3 months
7. severe hyperparathyroidism (intact parathyroid hormone > 1,000 pg/mL)
8. Pregnancy
9. Age < 18 years
10. History of asthma or eczema, any history of drug allergy, including allergy to
iron preparations
11. History of exposure to chemotherapy or cytotoxic drugs â?? 5-FU, hydroxyurea, hydroxycarbamide, methotrexate, trimethoprim,
colchicine, azathioprine
12. History of G-CSF use in the last 1 month
13. General anaesthesia with nitrous oxide in the last 1 month
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean haemoglobin <br/ ><br>Timepoint: 1 month <br/ ><br>
- Secondary Outcome Measures
Name Time Method