Effect of dadimadi ghrutha in primary hypothyroidism

Primary Hypothyroidism is an emerging health issue in India and worldwide 42 million people in India are suffering from Thyroid disease Thyroid abnormalities are diagnosed based on laboratory test results like Free thyroxine  and thyroid stimulating hormone TSH Anti TPO Anti thyroglobulin Constant use of conventional hormonal therapy is able to normalyse the laboratorial parameters of hypothyroidism But many of the symptoms persists and quality of the life of the affected has not been improved much So any intervention which reduce the severity of signs and symptoms of the disease will be highly beneficial to the society In Ayurvedic point of view the medicines are giving to activate digestive fire and fresh up the gut microbiota so the metabolism will be corrected and the thyroid gland also will start to function normally and patient will recover from hypothyroidism permanently

 The study design is interventional pre and post test with a sample size of 34 subjects fulfilling the inclusion and exclusion criteria Data collection will be done by doing blood investigations and clinical observations case proforma zulewski clinical score for hypothyroidism and Nottingham quality of life assessment Pachanamrutham kashayam 48 ml along with 2 shaddharanam tab morning and evening one hour before food shall be given to participants for 7 days From 8th day onwards 10 ml dadimadi ghrutham at bed time along with hot water shall be given for 90 days Data collected will be statistically analysed through appropriate tests and conclusions will be drawn