NL-OMON43152已完成不适用
Acute Nutritional Ketosis and Exercise in Glycogen Storage Disease type IIIa. - Acute Nutritional Ketosis in GSD IIIa
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •-GSD III confirmed with enzyme assay and/or AGL mutation analysis and GSD IIIa further specified as deficient debranching enzyme activity in muscle or clinical and/or biochemical signs of cardiac and/or skeletal muscular involvement.
- •-age 18-65
排除标准
- •-contraindications for MRI studies (assessed by standardised questionnaire as previously used in METC 08-267/K; see UMCG section F METC documents)
- •-inability to perform bicycle exercise.
- •-intercurrent illness which may influence exercise tolerance (anemia, musculoskeletal injury, or other undiagnosed illness under investigation).
- •-known coronary artery disease, positive history for angina or cardiomyopathy.
- •-insulin-dependent diabetes mellitus.
- •-loss of, or an inability to give informed consent.
- •-pregnancy or current breastfeeding.
- •-any other cause which in the opinion of the investigators, may affect the participant's ability to participate in the study
研究者
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