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临床试验/ISRCTN82040078
ISRCTN82040078已完成不适用

Do Xanthine Oxidase Inhibitors (XOI) have clinically useful anti-ischaemic effects in the treatment of angina pectoris? A double-blind, placebo controlled trial

niversity of Dundee (UK)0 个研究点目标入组 60 人开始时间: 2007年6月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Documented Coronary artery Disease (CAD) on angiography
  • 2. Chronic stable angina (greater than two months)
  • 3. Able to do Exercise Treadmill Test (ETT)
  • 4. Aged between 30 and 85 years

排除标准

  • 1. Contra-indication or unable to do ETT
  • 2. Already on allopurinol or previous allergy to allopurinol
  • 3. Left Ventricular (LV) ejection fraction less than 45%
  • 4. Myocardial Infarction (MI) or Acute Coronary Syndrome (ACS) over the last two months
  • 5. Change to anti-anginal therapy over the last month
  • 6. Percutaneous Coronary Intervention (PCI) or Coronary Artery Bypass Graft (CABG) within the last six months
  • 7. Significant renal or hepatic impairment
  • 8. On medication that may interact with allopurinol (e.g., warfarin)

研究者

发起方
niversity of Dundee (UK)

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