NCT04174495CompletedNot Applicable
Bone Fragility Evaluation by Dual X-Ray Absorptiometry (DXA) and CT-scan (vertebral Fracture and Scanographic Bone Attenuation Coefficient of the First Lumbar Vertebra SBAC-L1) in Obese Patients
Central Hospital, Nancy, France1 site in 1 country1,500 target enrollmentStarted: February 23, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 1,500
- Locations
- 1
- Primary Endpoint
- scanographic bone attenuation coefficient of the first lumbar vertebra SBAC-L1
Study Overview
Brief Summary
This research will study the bone fragility in obese patients, on DXA and CT-scan, in a transversal study. The investigators want also to study the specific risk factors of bone fragility in these obese patients (relationship between body composition on whole body on DXA, fat mass and its location, lean mass, weight loss after surgery and SBAC-L1), to improve the bone screening.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients followed at Nancy university hospital for a bariatric surgery
- •CT-scan and DXA performed before surgery, with maximum 1 year before the 2 exams
Exclusion Criteria
- •< 18 years
- •Protected adults
Outcomes
Primary Outcomes
scanographic bone attenuation coefficient of the first lumbar vertebra SBAC-L1
Time Frame: November 2019-September 2020
on axial section of the first lumbar vertebra, with a region of interest
Secondary Outcomes
- DXA: Bone mineral density BMD (spine, hip , femoral neck, wrist)(November 2019-September 2020)
- DXA: T-score(November 2019-September 2020)
- Vertebral fracture(November 2019-September 2020)
- DXA: lean and fat mass(November 2019-September 2020)
Investigators
Marine FAUNY
MD; Principal Investigator
Central Hospital, Nancy, France
Study Sites (1)
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