Comparison the effect of Aloe Vera and Benzydamine hydrochloride mouth rinses on mucositis caused by radiatio
Phase 2
- Conditions
- Mucositis.Acute radio dermatitis
- Registration Number
- IRCT2012072410377N1
- Lead Sponsor
- Baryj Essence Pharmaceutical Company
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
Minimum age: 18 years, diagnosed cancer in the head and neck region, the minimum therapeutic dose of 50 Gy, oral cavity is placed in the radiation field, the patient's ability to cooperate and use medications as directed. Exclusion criteria: Patients with a history of cancer treatment during the last year, patients with a history of food allergy, oral lesions including active infection, mouth ulcers before starting the radiation therapy, lack of patient willingness and cooperation to participate in the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mucositis grade. Timepoint: From Starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: questionnaire based on the Mucositis grade rating items from the World Health Organization (WHO).
- Secondary Outcome Measures
Name Time Method Mouth soreness. Timepoint: From starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: Questionnaire (Asking from patient).;Ulcer. Timepoint: From starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: Questionnaire (Observation).;Disability to swallowing solid food. Timepoint: From starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: Questionnaire (Asking from patient).;Disability to alimentation. Timepoint: From starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: Questionnaire (Asking from patient).;Erythema. Timepoint: From starting of radiation therapy, weekly during 6 weeks of treatment and 1 week after treatment. Method of measurement: Questionnaire (Asking from patient and observation).