Preconditioning Volatile Anesthesia in Liver Surgery

Completed

• Conditions: Anesthesia

• Registration Number: NCT01021228
• Lead Sponsor: University of Zurich

Brief Summary

The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Detailed Description

Comparing the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Study Timeline

• Study Start: 2008-08
• Primary Completion: 2009-10
• Study Completion: 2009-10
• Status Verified: 2009-11
• Study First Submitted: 2009-11-25
• Study First Submitted QC: 2009-11-25
• Last Update Submitted: 2009-11-25
• Study First Posted: 2009-11-26
• Last Update Posted: 2009-11-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 257

Inclusion Criteria

• > 18 years
• benign and malign disease
• any type of liver surgery
• inflow occlusion during the liver surgery

Exclusion Criteria

• < 18 years
• participation on other interventional and treatment randomized controlled trials,
• trauma of the liver
• liver cirrhosis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
peak ALT and AST levels representing the ischemia-reperfusion injury	post-operative

Secondary Outcome Measures

Name	Time	Method
length of hospital stay, length of ICU stay, blood loss and morbidity (post-operative complications)	post-operative

Trial Locations

Locations (1)

Universtiy Hospital of Zurich, Department of Visceral and Transplantation Surgery; 🇨🇭 Zurich, Switzerland