Traditional Versus Goal Directed Perioperative Fluid Therapy in High Risk Patients
Not Applicable
Terminated
- Conditions
- Postoperative Complications
- Registration Number
- NCT01473446
- Lead Sponsor
- Haukeland University Hospital
- Brief Summary
Is goal directed fluid therapy reducing postoperative complications in comparison to traditional fluid therapy for gastro surgical ASA III/IV patients?
The investigators compare two groups of patients: one group receives goal directed fluid therapy guided by LiDCOrapid stroke volume variation (SVV), the other gets the "traditional" fluids, ie the current regime.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Adult ASA class III & IV (high risk) patients
- >18 years
- scheduled for gastrointestinal surgery involving laparotomy
- Both elective and emergency cases
Exclusion Criteria
- Atrial fibrillation
- Mental impairment, unable to give informed consent
- Severe aortic or mitral stenosis
- Type of surgery: Liver surgery, transthoracic oesophagectomy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Postoperative complications 5 days after surgery
- Secondary Outcome Measures
Name Time Method Renal function 5 days after surgery defined by RIFLE criteria
Complications until discharge and readmission within 30 days 3 month after surgery Mortality within 30 days and 3-month after surgery 3 month after surgery Length of hospital stay 3 month after surgery Vasoactive agents need 3 month after surgery Difference in the number of patients in need of vasoactive agents, during surgery and in the postoperative period.
Trial Locations
- Locations (3)
Oulu University Hospital, Department of Anesthesia and Intensive Care
🇫🇮Oulu, Finland
Haukeland University Hospital
🇳🇴Bergen, Norway
Stavanger Universityhospital, Division for medical service, anesthesia and intensive care
🇳🇴Stavanger, Norway
Oulu University Hospital, Department of Anesthesia and Intensive Care🇫🇮Oulu, Finland