Effect of co-administration of quercetin on the endothelial dysfunction after continuous treatment of nitroglycerin in Japanese volunteers with aldehyde dehydrogenase2 2 polymorphism: randomized crossover trial - Effect of quercetin on the endothelial dysfunction after nitroglycerine treatment in Japanese volunteers with ALDH2 2 polymorphism

SOUSEIKAI Fukuoka Mirai Hospital, Clinical Research Center0 个研究点目标入组 24 人开始时间: 2018年8月6日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1.History of cardiovascular disease 2.Severe hepatic or renal dysfunction 3.Volunteers who received other clinical study drug within 30 days 4.Woman who is pregnant or possibly be pregnant 5.History of severe allergy or allergic reaction to the drugs which are used in the present study 6.History of heart disease, glaucoma, peptic ulcer and aspirin-induced asthma 7.volunteers who have smoking habit 3 months before the start of this study 8.On medical treatment (exclude NSAIDs and sleeping pills taken as needed) 9.On medical treatment of phosphodiesterase 5 or agents with guanylate cyclase stimulating effect 10.systolic blood pressure<90 mmHg 11.Body weight <40 kg or >90 kg 12.Not appropriate to this study by other reasons

发起方

SOUSEIKAI Fukuoka Mirai Hospital, Clinical Research Center