IRCT201701172709N43
Completed
Phase 2
The effect of oral quercetin supplement intake on oxidative markers , serum iron, liver enzymes and inflammatory indices in ß-thalassemia major patients,a double-blind placebo-controlled clinical trial
Vice chancellor for research, Iran University of Medical Sciences0 sites84 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- beta thalassemia major.
- Sponsor
- Vice chancellor for research, Iran University of Medical Sciences
- Enrollment
- 84
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 to 30 year old male and female beta thalassemia major patients; Inclination to cooperate and signing the written informed consent; A minimum of 2 years of blood transfusion history; blood specimen collection 20 days after the last blood transfusion; Regular and peculiar iron\-chelating therapy with desferrioxamine; Vitamin C supplement intake with desferrioxamine; Serum ferritin level between 2500 to 3500 ng/ml
- •Exclusion criteria:
- •Uncontrollable and life threatening complication due to due to the supplement intake; A change in type or amount of the iron chelator; Pregnancy or lactation; Splenectomy; Hepatitis infection and other metabolic or infectious diseases; Less than 80% compliance of supplement intake; Consumption of drugs that interfere with quercetin; Drinking more than 500 mg/day of beverages rich in flavonoids; Smoking or alcohol consumption
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 2
Quercetin on thalassemia induced depressioIRCT20091114002709N46Iran University of Medical Sciences84
Completed
Phase 3
Effect of Quercetin supplementation on inflammatory and Creatinine kinase responses after a swimming session in girlsIRCT20200804048307N1Islamic Azad University20
Completed
Not Applicable
Effect of co-administration of quercetin on the endothelial dysfunction after continuous treatment of nitroglycerin in Japanese volunteers with aldehyde dehydrogenase2 *2 polymorphism: randomized crossover trialangina pectorisJPRN-UMIN000033639SOUSEIKAI Fukuoka Mirai Hospital, Clinical Research Center24
Completed
Not Applicable
Effects of quercetin ingestion during 6 weeks of strength training on neuromuscular activity in the older adults.JPRN-UMIN000053019Chukyo University30
Completed
Phase 2
The effect of co-administration of quercetin supplemented cardiac cardiovascular system with cardiotoxicity of doxorubicin in patients with breast cancerPatients with Breast Cancer.Breast, unspecifiedIRCT20190303042892N1Rasht University of Medical Sciences100