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临床试验/NCT01788098
NCT01788098已完成不适用

Rheumatoid Arthritis Susceptibility Genes in Austrian and Slovak Population

Slovak Academy of Sciences1 个研究点 分布在 1 个国家目标入组 790 人开始时间: 2009年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
790
试验地点
1
主要终点
Genetic association

研究概览

简要总结

The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia. Variations in several genes associated with RA will be evaluated. The second aim is to assess functional changes in immune cells from selected patients and their evaluation together with genetic background. The project has observational character without any intention to change the treatment of RA patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • rheumatoid arthritis or healthy

排除标准

  • 未提供

结局指标

主要结局

Genetic association

时间窗: 1 day

Association of selected single nucleotide polymorphisms with rheumatoid arthritis.

次要结局

  • Peripheral blood mononuclear cells reactivity(1 day)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Stefan Zorad

Head of Laboratory

Slovak Academy of Sciences

研究点 (1)

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