Visual Outcome After Transsphenoidal Surgery for Pituitary Macroadenoma

Completed

• Conditions: Optic Chiasm Disorder; Pituitary Tumor

• Registration Number: NCT03363126
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

Endoscopic endonasal transsphenoidal surgery is a procedure for the treatment of pituitary macroadenomas that cause visual impairment through optic chiasm compression. The aim of this retrospective study is to describe visual outcome after this procedure.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-01
• Primary Completion: 2016-02-10
• Study Completion: 2016-06-20
• Status Verified: 2017-11
• Study First Submitted: 2017-11-30
• Study First Submitted QC: 2017-11-30
• Last Update Submitted: 2017-11-30
• Study First Posted: 2017-12-06
• Last Update Posted: 2017-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

• Pituitary tumor causing optic chiasm compression (documented on MRI or CT-scan)
• Visual impairment caused by chiasm compression
• Treatment by transsphenoidal endonasal surgery
• Treatment in the Rothschild Foundation (Paris) between 2009 and 2013

Exclusion Criteria

• Ophtalmologic condition other than optic chiasm compression

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-operative gain in visual acuity	six months	Difference between pre-operative and post-operative visual acuity, expressed in LogMAR