Double-blind, placebo-controlled crossover trial of inhaled oxygen in the treatment of acute cluster headache
Completed
- Conditions
- Cluster headacheNervous System Diseases
- Registration Number
- ISRCTN94092997
- Lead Sponsor
- BOC Ltd (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
1. Active Cluster headache
2. Attack duration between 45 minutes and three hours
Exclusion Criteria
1. Pregnant and lactating women will be excluded
2. Patients with moderate to severe chronic obstructive pulmonary disease will be excluded as the high-dose high-flow oxygen may affect their hypoxic respiratory drive.
3. Patients who cannot tolerate the oxygen mask in the correct fitting will be excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients pain free after 15 minutes of treatment comparing oxygen and air.
- Secondary Outcome Measures
Name Time Method 1. Rendering the patient pain free at 30 minutes <br>2. Reduction in pain scale at 15, 30, 45 and 60 minutes <br>3. Need for rescue medication from 15 minutes after treatment <br>4. Overall response to the treatment and overall functional disability <br>5. Effect on associated symptoms