Evaluation of magnesium sulphate gargle for post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Department of Anaesthesia
- Enrollment
- 52
- Locations
- 1
- Primary Endpoint
- TO EVALUATE THE INCIDENCE AND SEVERITY OF POST OPERATIVE SORE THROAT IN PATIENTS RECEIVING PREOPERATIVE GARGLE OF MAGNESIUM SULPHATE 20MG/KG DILUTED UPTO 30ML WITH NORMAL SALINE UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATION
Study Overview
Brief Summary
Primary objective - To evaluate the incidence and severity of post- operative sore throat in patients receiving preoperative gargle magnesium sulphate 20 mg/kg diluted upto 30ml with normal saline
undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubation.
Secondary objective - To evaluate incidence and severity of cough and hoarseness of voice in patients receiving preoperative gargle with magnesium sulphate 20mg/kg diluted upto 30ml with normal
saline in above study population.
Study Design
- Study Type
- Interventional
- Allocation
- Permuted block randomization, fixed
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •belonging to ASA physical status 1 and 2 undergoing laparoscopic surgery under general anaesthesia with endotracheal intubation.
Exclusion Criteria
- •patients with difficult airway.
- •patients with a history of pre-operative sore throat , oral surgeries, asthma , diabetes, chronic obstructive pulmonary disease , head and neck surgeries.
- •patient with known allergies to study drug and rescue drugs.
- •duration of surgery <1hour and >4 hours.
- •patient consuming non steroidal anti inflammatory drugs within 24hours prior to the surgery or on systemic / topical steroid therapy or taken steroid drugs within 5 days prior to surgery.
Outcomes
Primary Outcomes
TO EVALUATE THE INCIDENCE AND SEVERITY OF POST OPERATIVE SORE THROAT IN PATIENTS RECEIVING PREOPERATIVE GARGLE OF MAGNESIUM SULPHATE 20MG/KG DILUTED UPTO 30ML WITH NORMAL SALINE UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATION
Time Frame: AT 0hr, 2hr, 4hr and 24hr
Secondary Outcomes
- To evaluate incidence and severity of cough and hoarseness of voice in patients receiving preoperative gargle with magnesium sulphate 20mg/kg diluted upto 30ml with normal saline .(at 0hr, 2hr, 4hr and 24hr)