Evaluation of magnesium sulphate gargle for post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- TO EVALUATE THE INCIDENCE AND SEVERITY OF POST OPERATIVE SORE THROAT IN PATIENTS RECEIVING PREOPERATIVE GARGLE OF MAGNESIUM SULPHATE 20MG/KG DILUTED UPTO 30ML WITH NORMAL SALINE UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATION
研究概览
简要总结
Primary objective - To evaluate the incidence and severity of post- operative sore throat in patients receiving preoperative gargle magnesium sulphate 20 mg/kg diluted upto 30ml with normal saline
undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubation.
Secondary objective - To evaluate incidence and severity of cough and hoarseness of voice in patients receiving preoperative gargle with magnesium sulphate 20mg/kg diluted upto 30ml with normal
saline in above study population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, fixed
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •belonging to ASA physical status 1 and 2 undergoing laparoscopic surgery under general anaesthesia with endotracheal intubation.
排除标准
- •patients with difficult airway.
- •patients with a history of pre-operative sore throat , oral surgeries, asthma , diabetes, chronic obstructive pulmonary disease , head and neck surgeries.
- •patient with known allergies to study drug and rescue drugs.
- •duration of surgery <1hour and >4 hours.
- •patient consuming non steroidal anti inflammatory drugs within 24hours prior to the surgery or on systemic / topical steroid therapy or taken steroid drugs within 5 days prior to surgery.
结局指标
主要结局
TO EVALUATE THE INCIDENCE AND SEVERITY OF POST OPERATIVE SORE THROAT IN PATIENTS RECEIVING PREOPERATIVE GARGLE OF MAGNESIUM SULPHATE 20MG/KG DILUTED UPTO 30ML WITH NORMAL SALINE UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATION
时间窗: AT 0hr, 2hr, 4hr and 24hr
次要结局
- To evaluate incidence and severity of cough and hoarseness of voice in patients receiving preoperative gargle with magnesium sulphate 20mg/kg diluted upto 30ml with normal saline .(at 0hr, 2hr, 4hr and 24hr)