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Registry for Severe ROP and Treatment on Visual Outcomes

Completed
Conditions
Retinopathy of Prematurity
Registration Number
NCT01559571
Lead Sponsor
Pediatrix
Brief Summary

The purpose of this study is to determine what factors influence the visual outcomes of infants with severe retinopathy of prematurity (ROP) and to monitor the outcomes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
324
Inclusion Criteria
  • Documentation of informed consent and authorization
  • Inborn and those admitted within 7 days of birth
  • Infant with a diagnosis of stage 2 ROP or higher
  • Site ability to plan close ophthalmological follow-up due to significant and persistent ROP
  • Parents must agree to report outcomes following each ophthalmological visit and overall outcomes for up to five (5) years of age
  • Ability to obtain follow-up data on outcomes if the child is transferred to another facility
  • No known major congenital anomalies
Exclusion Criteria
  • ROP stage 1 or less
  • Parents unwilling to participate in follow-up
  • Major congenital anomalies

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identification of visual acuity in subjects who were treated for ROPFive year follow-up
Secondary Outcome Measures
NameTimeMethod
Recurrence of stage 3+ retinopathy of prematurity in one or both eyes in zone I or posterior zone II Recurrence of stage 3+ retinopathy of prematurity in one or both eyes in zone I or posterior zone IIFive year follow-up

Trial Locations

Locations (2)

Memorial Hospital of South Bend

🇺🇸

South Bend, Indiana, United States

Summerlin Hospital Medical Center

🇺🇸

Las Vegas, Nevada, United States

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