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Clinical Trials/NCT05804188
NCT05804188
Recruiting
Not Applicable

CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation

Insel Gruppe AG, University Hospital Bern8 sites in 5 countries105,000 target enrollmentJanuary 8, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intubation Complication
Sponsor
Insel Gruppe AG, University Hospital Bern
Enrollment
105000
Locations
8
Primary Endpoint
Number of patients with critical events related to intubation
Status
Recruiting
Last Updated
11 months ago

Overview

Brief Summary

The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites. Furthermore, the study will investigate the used intubation techniques and identify possible improvement measures to increase patient safety.

Detailed Description

It is a prospective observational multi-centre study collecting health related patient data over a period of three months. This serves best the study's purpose to detect the incidence and nature of problems related to tracheal intubation and how such problems are handled with the aim to further improve patient safety. During the observational period the anaesthesia staff in charge will complete a screening questionnaire for critical events associated with tracheal intubation for every patient undergoing general anaesthesia with tracheal intubation. If no critical events arise there are no further requirements. If a critical event occurs, the anaesthesia provider will complete a more detailed questionnaire which includes more questions about what exactly happened. Patient characteristics will be extracted from the anaesthesia records. The investigators will extract such data for all patients undergoing tracheal intubation and additional data for those with critical events. The research will not intervene with the clinical conduct of patient care. The collected health related data will be transferred to an electronic research data base. In this data base data will be encoded. Every patient with a critical event will be followed up as described above.

Registry
clinicaltrials.gov
Start Date
January 8, 2024
End Date
December 2025
Last Updated
11 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • All paediatric patients requiring tracheal intubation, performed by the anaesthesia team for procedures or interventions requiring general anaesthesia
  • Patients from 0 - 16 years of age.
  • Informed or general consent given, according to the relevant ethics committee statement.

Exclusion Criteria

  • Refusal to give consent or withdrawal of consent if such is required by the relevant ethics committee.
  • Patients \>16 years

Outcomes

Primary Outcomes

Number of patients with critical events related to intubation

Time Frame: Maximum of 30 days

Primary study outcome is the incidence of anaesthesia cases with critical events associated with endotracheal intubation requiring intervention from the start of anaesthesia until the discharge of the patient from the post-anaesthesia care unit or end of anaesthesia (defined as handover to the paediatric or neonatal intensive care unit, the ward or discharge home straight from anaesthesia care) in children aged 0 - 16 years. Facultatively for those who do not have capacity the acquisition of data stops at the end of anaesthesia (defined as handover to the post-anaesthesia care unit).

Secondary Outcomes

  • Number of patients with laryngospasm(1 hour)
  • Number of patients with bronchospasm(1 hour)
  • Number of patients with airway bleeding(1 hour)
  • Number of patients with can't intubate, can't oxygenate (CICO) situation(1 hour)
  • Number of patients with severe hypoxemia(1 hour)
  • Number of patients with severe bradycardia(1 hour)
  • Number of patients with stridor after extubation(1 hour)
  • Number of patients with pulmonary aspiration(1 hour)
  • Number of patients with esophageal intubation(1 hour)
  • Number of patients with obstruction of tracheal tube(1 hour)
  • Number of patients with pneumothorax/ pneumomediastinum(1 hour)
  • Number of patients with severe bradycardia/Cardiac arrest(1 hour)
  • Number of patients with negative pulmonary oedema(1 hour)

Study Sites (8)

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