Lung And Diaphragm ultrasonography And Rapid Shallow Breathing Index As A Predictor For Successful Weaning From Mechanical Ventilation In Icu Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- To evaluate the Diaphragmatic Thickening Fraction (DTF) as a predictor for successful weaning in ICU patients
研究概览
简要总结
This is a prospective observational study, predicting successful weaning in mechanically ventilated patients admitted in icu of Lok Nayak Hospital New Delhi who are undergoing spontaneous breathing trial by measuring diaphragm thickening fraction and diaphragm excursion and lung ultrasound score by doing diaphragm and lung ultrasonography respectively, rapid shallow breathing index, MEP and MIP at specified time of spontaneous breathing trial. Following this patient will be extubated and assessed for the success of weaning and the need for need of non-invasive ventilation or re intubation for 24 hours by doing arterial blood gas analysis at 1st and 6th hour post extubation.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 18 to 65 years
- •Mechanical ventilation for minimum 48 hours an.
排除标准
- •Patients with history of neuromuscular disease
- •Patients with history suggestive of diaphragmatic dysfunction
- •Patients with chest tube in situ
- •Patients with pneumothorax & pneumomediastinum
- •Patients with chronic obstructive pulmonary disease
- •Pregnant Patients
- •Patients with known heart failure.
结局指标
主要结局
To evaluate the Diaphragmatic Thickening Fraction (DTF) as a predictor for successful weaning in ICU patients
时间窗: 30 minutes from spontaneous breathing trial
次要结局
- To evaluate the Diaphragmatic Excursion (DE), Lung Ultrasound Score (LUS) & Rapid Shallow Breathing Index (RSBI) as a predictor for successful weaning in ICU patients(Rapid Shallow Breathing Index (RSBI) at 5 & 30 minutes of spontaneous breathing trial)
- Maximum expiratory pressure (MEP) & Maximum Inspiratory Pressure (MIP) to predict successful weaning(5 minutes & 30 minutes from spontaneous breathing trial)
- The number of patients requiring Non-Invasive Ventilation (NIV) or reintubation within 24 hours of extubation(Within 24 hours from extubation)
- Time to reintubation/non-invasive ventilation: Time interval between the point of extubation & the point of non-invasive ventilation/reintubation if done.(Within 24 hours from extubation)