Clinical trial for investigating social cognition in healthy participants and patients with either mild cognitive disorder or alzheimer disease.

Recruiting

Conditions: F00.9
Mild cognitive disorder
F06.7
Dementia in Alzheimer disease, unspecified

Registration Number: DRKS00012441

Lead Sponsor: Klinik und Poliklinik für Psychiatrie und Psychotherapie; Zentrum für Gedächtnisstörungen (ZfG)/ Center for memory disorders; Universitätsklinikum Köln

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 120

Inclusion Criteria

Inclusion criteria patients:
- diagnosed amnestic MCI or alzheimer disease (criterias following the S3-dementia-guideline)
- MCI-patients: detailed neuropsychological Investigation within the last 12 month
- elaborate explanatory meeting and written agreement
- Age: older than 50 years
- good knowledge of german language
- Minimum 6 years of education or the equivalent of alphabetisation

Inclusion criteria controlgroup:
- unimpaired social cognition
- elaborate explanatory meeting and written agreement
- Age: 20 - 35 years or older than 50 years
- good knowledge of german language
- Minimum 6 years of education or the equivalent of alphabetisation

Exclusion Criteria

Exclusion criteria patients:
- urgent psychological or neurological diseases (clinical relevant episode of depression, geriatric depression scale, scoring 11 Points or higher)

Exclusion criteria controlgroup:
- dementia or mild cognitive impairment
- ability of social cognition under the range according to age, gender and education
urgent psychological or neurological diseases (clinical relevant episode of depression, geriatric depression scale, scoring 11 Points or higher or BDI I-II > 20 points)

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Social cognition, investigated with the following tests:<br><br>The Karolinska directed emotional faces (KDEF): 28 Pictures of male and female faces showing the Basic emotions; decoding emotions <br><br>Reading mind in the eyes-test: 36 Pictures of male and female eyes; Decoding emotions<br><br>MASC (Movie for the Assessment of Social Cognition): Video material and following questionnaire; theory of mind <br><br>Theory of mind Picture Stories Task: Sorting 6 picture stories in the right order and following questionnaire

Secondary Outcome Measures